Yes! Many of our customers enjoy using Ready Rig in handheld mode, especially with one arm, as it allows for increased range of motion during side to side panning while still providing weight support. Be sure to have a solid mounting point on top of the camera - we recommend using a top handle or third party camera cage.
If you have any specific compatibility questions, let us know and can get back to you with our recommendations.
If you would like to learn more, we wrote a tutorial on handheld setup.